Ei-ichi Negishiwas born on July 14, 1935 in Hsinking, capital of Manchukuo, now Changchun of China.

He graduated from the University of Tokyo in 1958 and did his internship at Teijin. He went on to study in the United States and obtained his PhD from University of Pennsylvania in 1963 under the supervision of Prof. Allan R. Day. He became a postdoctoral researcher at Purdue University where he worked with Nobel Laureate Herbert C. Brown. Thereafter he went on to work at Syracuse University. Most of his career was at Purdue University, United States.
Negishi is best known for his discovery of the Negishi Coupling. He was awarded the 2010 Nobel Prize in Chemistry for palladium catalyzed cross couplings in organic synthesis jointly with Prof. Richard F. Heck and Prof. Akira Suzuki.

Prof. Ei-ichi Negishi in the B.M. Birla Science Prize Award Ceremony at the B.M. Birla Science Centre on January 09, 2013.